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Manufacturer: Celebrex
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Celebrex
Celebrex (CELECOXIB) is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation
Uses
The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any of our products. Celebrex is a non-steroidal anti-inflammatory drug (NSAID) that represents a huge breakthrough in the treatment of pain, inflammation, and stiffness of arthritis.
How to take
- You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. - In Osteoarthritis, the recommended dose for CELEBREX is 100 - 200 mg a day. CELEBREX delivers 24-hour relief from a once-daily dose of 200 mg. - In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night. CAN I TAKE CELEBREX IF I AM TAKING OTHER MEDICATIONS? If you are one of the many people who take low-dose aspirin for the prevention of heart attack or stroke, you can still take CELEBREX. However, taking CELEBREX and aspirin together can increase your risk for developing stomach ulcers compared to taking CELEBREX alone. CELEBREX is not a substitute for aspirin for heart attack or stroke prevention. CAN I TAKE CELEBREX IF I AM PREGNANT? In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. IS CELEBREX A SUBSTITUTE FOR CORTICOSTEROIDS? NO. CELEBREX cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of this medicine may lead to exacerbation of corticosteroid-responsive illness. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue this medication. INCLUDE IN YOUR MEDICAL HISTORY/PERSONAL PROFILE : - If you are pregnant or plan to become pregnant. Celebrex should not be used in late pregnancy because it may harm the fetus. - If you are breast-feeding or plan to breast-feed. It is not known whether Celebrex is passed through to human breast milk and what its effects could be on a nursing child. - If you have kidney disease. - If you have liver disease. - If you have heart failure. - If you have high blood pressure. - If you have had an allergic reaction to aspirin or other NSAIDs. - If you have had a serious stomach problem (ulcers) in the past.
Side effects
Serious but rare side effects that have been reported in patients taking CELEBREX are delineated below : - Serious stomach problems, such as stomach and intestinal bleeding, can occur with or without warning symptoms. These problems, if severe, could lead to hospitalization or death. Although this happens rarely, you should watch for signs that you may have this serious side effect. - Serious allergic reactions including swelling of the face, lips, tongue, and/or throat which may cause difficulty breathing or swallowing and wheezing occur rarely but may require treatment right away. Severe skin reactions have also been reported. - Serious kidney problems occur rarely, including acute kidney failure and worsening of chronic kidney failure. - Severe liver problems, including hepatitis, jaundice and liver failure, occur rarely in patients taking NSAIDs, including CELEBREX. Symptoms of liver problems include nausea, tiredness, itching, tenderness in the right upper abdomen, and flu-like symptoms. In addition, the following side effects have been reported: anxiety, confusion, depression, hair loss, hallucinations, increased levels of potassium in the blood, low blood cell counts, palpitations, pancreatitis, tingling sensation, unusual headache with stiff neck (aseptic meningitis), vertigo.
Precaution
Do not take CELEBREX if you: - have had an allergic reaction such as asthma attacks, hives, or swelling of the throat and face to aspirin or other NSAIDs (for example, ibuprofen and naproxen). - have had an allergic reaction to celecoxib, which is the active ingredient of CELEBREX any of its inactive ingredients.
Drug interactions
Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. CELEBREX has significant drug interactions with : - Methotrexate (a medicine used to suppress the immune system). - Warfarin (a blood thinner). - Rifampin (an antibiotic). - ACE inhibitors (medicines used for high blood pressure and heart failure). - Lithium (a medicine used to treat a certain type of depression).
Missed dose
If you miss a dose of Celebrex, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the amount of Celebrex used to catch up.
Storage
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children.

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